CIB academics presented their research at congress on mitochondria and cancer in Prague

10-04-19

Dr. Julio César Cárdenas and Alenka Lovy were the only representatives of Chile in the event held in mid-September.

The role of mitochondria in cancer was the central theme of the congress held in mid-September in Prague, Czech Republic, where researchers from the Center for Integrative Biology (CIB) of the Universidad Mayor, Julio César Cárdenas and Alenka Lovy participated.

The Doctors presented their work on the regulation of mitochondria through calcium and what is its impact on tumor growth.

My presentation was a particular group of tumors that shows a special sensitivity to this regulation. While in the vast...

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Director of the CIB U. Mayor participates in research that created a method that successfully slows the progress of Parkinson's

09-24-2019

A new strategy to stop Parkinson's disease at an early stage is the result of three years of collaborative research between Dr. Felipe Court, director of the Center for Integrative Biology (CIB) of the Universidad Mayor and Claudio Hetz, director of the Millennium Institute of Biomedical Neuroscience (BNI) of the Faculty of Medicine of the Universidad de Chile.

The technique consists in blocking the destruction of the axon with a drug, a segment of the neuron similar to an extension or branching that allows communication between different brain cells.

Parkinson's disease that causes loss of motor control, occurs when dopaminergic neurons stop functioning or die. These cells ...

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U. Mayor is awarded $ 240 million and becomes the only private institution among the winners of the Fondequip.

09-09-2019

The project, presented by academics from the Center for Integrative Biology, was one of 28 selected from 168 applicants, and will allow the acquisition of state -of- the art microscope, which will also be the first of its kind present in a university in South America.

Great news. A few days ago it was announced that the Universidad Mayor was the only private institution to win the Fondequip Medium Scientific and Technological Equipment Contest, which each year the National Commission for Scientific and Technological Research, Conicyt.

Our house of studies was awarded $ 240 million, the highest amount distributed by the entity, which will al...

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Universidad Mayor will sponsor the World Congress on Aging that will host Chile.

09-05-2019

The event will take place between November 18 and 21 in Puerto Varas, and is part of a series of continental meetings on geoscience, a discipline that seeks to intervene to slow down the process of natural deterioration of the human organism.

During November, Chile will host the World Congress “International Perspectives on Gerocieties 2019”, organized by the Center for Gerocience, Mental Health and Metabolism (GERO) and sponsored by the Universidad Mayor.

The activity is part of a series of meetings sponsored by the network of Nathan Shock Center centers of excellence, which have been held in the United States, Australia, Spain, Israel, Singapore and China on this ...

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Researchers from Uruguay and Mexico carry out an internship at the Center for Integrative Biology to study cell aging.

09-04-2019

Sofía Ibarburu, Andrés Cawen and Daniel Moreno were interested in the work done by the unit's director, Dr. Felipe Court.

Two Uruguayan researchers and a Mexican do an internship at the Center for Integrative Biology (CIB) of the Universidad Mayor, with the aim of studying cell aging.

Sofía Ibarburu, who works at the Pasteur Institute in Montevideo on neurodegenerative diseases, arrived in Santiago interested in the work of the center's director, Dr. Felipe Court. “He went to present a job to Uruguay and a project on exosomes caught my attention and I contacted him,” he said.

The young woman said that her idea “is to study the senescence of a population of cells that...

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New finding adds evidence on the role of the microbiota in health: The state of the bacterial flora influences cancer survival

08-19-2019

A study led by a Chilean scientist showed that greater diversity in the body's bacteria drives an increase in life in cases of pancreatic cancer.

Pancreatic cancer is an aggressive disease. In most cases, it does not respond to available treatments and causes thousands of deaths each year.

But, on the other hand, science has advanced in discovering the relationship between bacterial flora - known as microbiota - and health. And precisely cancer is a condition that has been associated with the composition of these microbes.

Now, new research led by Chilean scientist Erick Riquelme, a researcher at the Center for Integrative Biology at the Mayor University, has shown th...

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2020 Accreditation and increase of indicators: Review the keys of the Third Meeting of Researchers U. Mayor

14-08-2019

The event brought together 70 academics on the Huechuraba campus, where, for example, the number of indexed publications and the challenges that will bring the process to certify our quality in the Research area were highlighted.

A call to join and actively participate in the 2020 Accreditation Process was made by the Rector of the Universidad Mayor, Rubén Covarrubias Giordano, who led the inauguration of the Third Meeting of Researchers 2019.

The activity, held this Friday, August 9 at the Huechuraba campus, served both to highlight the results achieved in 2018 in the Research area, and to discuss the challenges that the process that will certify our quality for the fourth...

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Test gene therapy in Huntington's disease

07-31-2019

Claudio Hetz and René Vidal used a method that replaces drugs in mice.

In Claudio Hetz's imagination, gene therapy is the simile of a vehicle that transports the essential merchandise to survive. "It is avant-garde, well emerging. Instead of using a pill with a chemical compound, a gene is used as a therapeutic agent," explains the director of the Millennium Institute of Biomedical Neuroscience of the Faculty of Medicine of the University of Chile.

The doctor of Biomedical Sciences uses this technique in a specific place in the brain. In simple, it introduces a gene wrapped in a virus, which is responsible for infecting damaged neurons. "Think of a capsule dru...

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Scientist U. Mayor organized symposium on glial cells in Portugal

07-18-19

Dr. Felipe Court was the only representative who had the opportunity to present at the XIV European Meeting of Glial Cells in Health and Disease, among hundreds of applicants.

The director of the Center for Integrative Biology (CIB) of the Universidad Mayor, Dr. Felipe Court, organizes a symposium on glial cells and its effect on neuronal circuits, within the framework of the XIV European Meeting of Glial Cells in Health and Disease. in the city of Porto, Portugal, which gathered more than a thousand people.

This congress is the largest in the world associated with the study of the nervous system of a perspective not focused on the neuron but on the glial cells, whi...

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U. Mayor Scientists integrate team that delivered a national proposal to prevent dementias

06-24-2019

Doctors Felipe Court and Julio Cesar Cardenas, members of the Center for Integrativa Biology (CIB),participate in the development of a document published in ther former Congress, that deliver an interdisciplinary proposal to approach this problem and that has been prepared by 70 researchers from Chile and Foreign.

Currently, 200 million people have some kind of dementia in the country. However, this pathology is not only affect the patient, but also their families and caregivers. Thus, and due to the fact that the Chilean population is aging, various forecasts indicate this problem is becoming more complex over the years.

Faced with this challenge, a group of more than 70 n...

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Artist and Scientist transform photographs of neural networks into works of art

06-18-2019

“Cultivo", the exhibition by Juana Gomez, is based on the work of Dr. Felipe Court, principal of the Center for Integrative Biology of the U. Mayor.

The concepts of Art and Science came together to give life to the work of the renowned national artist, Juana Gomez, whose work has been cataloged as a true anatomical study, since it links disciplines such as mathematics and biology with photography, drawing and the embroidery.

Thus, her creation, called "Cultivo", arises from his dialogues with Dr. Felipe Court, principal of the Center for Integrative Biology (CIB) of the U. Mayor, who has focused his work on investigating how the nervous system works and why neurons die.

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Center for Integrative Biology presented advances in its research on Alzheimer's and ELA

05-29-2019

The activity, carried out in the Huechuraba campus, sought to disseminate results and obtain complementary information that provides new perspectives for the studies that are under development.

The research seminars are a platform and, at the same time, an opportunity for the scientific community of the U. Mayor to communicate the progress and results of their research. In this context, on May 23 and 24, the Center for Integrative Biology (CIB) brought together, on the Huechuraba campus, students, academics and the general public to approach two issues in the field of health.

Dr. Ute Woehlbier, associate professor at the Center for Integrative Biology and organizer of the ac...

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U. Mayor and Huawei agree joint collaboration on technology and research

05-27-2019

In a significant event for our institution, the Rector Rubén Covarrubias Giordano and the Executive Director of Huawei Chile, Dou Yong, signed an agreement that becomes an exchange of ideas, technical services and artificial intelligence, transcendent topics for the university.

Cloud services, quantum computing and artificial intelligence are some of the areas in which the Universidad Mayor and Huawei Chile can work together as of this year, thanks to the memorandum of understanding that both organizations signed this Wednesday May 22 in dependencies of the rectory.

The meeting was headed by Rector Rubén Covarrubias Giordano and Huawei Chile Executive Director, Dou Yong, who...

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Researchers from the Center for Integrative Biology (CIB) of the Universidad Mayor Participate in a publication in the high impact journal Nature Cell Biology.

05/23/2019

Drs. Cesar Cardenas and Felipe Court, principal investigators of the CIB, participated in a publication that investigates the association between the mitochondria and the endoplasmic reticulum, two key cellular organelles for the energy control of the cell.

Download (PDF): Paper Nature Cell biology

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Researcher published article in prestigious journal Nature Communications together with academics from Belgium

05-14-2019

Dr. Diego Rojas Rivera, from the Center for Integrative Biology U. Mayor, recently published an article describing the complexity of the mechanisms of regulation of cell death, it could impact on different anti-inflammatory therapies.

A pioneering research team in Chile, formed at the eaves of the Center for Integrative Biology (CIB) of the Universidad Mayor, is beginning to see its first results.

In this case, we refer to Dr. Diego Rojas Rivera, who recently participated with the Inflammation Research Center of the University of Ghent (Belgium), in the development of an article that was published in the scientific journal Nature Communications and describes mechanisms of regu...

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Michael J. Fox Foundation supports Chilean laboratory to develop therapy against Parkinson's.

The Michael J. Fox Foundation for Research of the Parkinson’s gave a competitive fund of more than one hundred million pesos to the Center for Integrative Biology of the Universidad Mayor, directed by Felipe Court, to research for a possible therapy against the neurodegenerative disease that It has no cure.

"They are a study where new mechanisms that contribute to Parkinson's disease are discovered," says Court, biologist and doctor of Neuroscience.

“We found in the laboratory, that blocking a mecanism of the neurons, when they die, they produce the disease, we could block the development or progression of the symptoms associated with the dis...

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Universidad Mayor Researcher detailed the main behaviors that would boost the onset of brain diseases

At the second conference of "The Route of Thought", PhD. René Vidal, researcher at the CIB (Center for Integrative Biology), called for a healthy diet and constant physical and intellectual activity. In addition, he explained that the use of probiotics could help prevent pathologies such as Alzheimer's or Parkinson's.

"The route of thought", which is the cycle of speeches with which the Direction Public Engagement is looking to bring scientific topics to the community, had its second conference this year. This time, the protagonist was PhD. René Vidal, researcher at the Center for Integrative Biology (CIB) Universidad Mayor, who e...

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Director of the CIB awarded project of the Michael J. Fox Foundation to study new therapeutic targets against Parkinson's

PhD. Felipe Court explained that his proposal is to block pharmacologically the process of neuronal degeneration to stop the progression of the disease.

PhD. Felipe Court, director of the Center for Integrative Biology (CIB) of the Universidad Mayor, was awarded an important project of The International Michael J. Fox Foundation to study new therapeutic targets for Parkinson's disease. These projects are open to researchers around the world and are highly competitive.

The scientist explained that in his laboratory has been investigating the cellular mechanisms involved in neuronal deterioration in Parkinson's disease, which affects the nervous system and results in loss of ...

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The prevention of Parkinson's would be in the intestine

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What Do We know about diseases that affect the brain? Scientific research as a motor of change in society

PhD. Rene Vidal, Researcher of the Center of Integrative Biology of the Universidad Mayor. PhD in science-biology and cellular.

The brain functions as a complex network, organized temporally and spatially. This organ, as it ages, is losing its ability to adapt to the paths it experiences daily. In Addition, it decreases its size and thus the neural communications (synapses), which are key to the normal functioning of this. On the second date of the cycle of the Route of thought, the academician of the Center of Integrative Biology U. Major, PhD. Rene Vidal, detailed the scientific efforts to create new tools that reverse or delay this process, in order to avoid the emergence of d...

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PHD in neurobiology began its version 2019 with talks by Outstanding Scientists

In the encounter participated and exposed the National Science Award 2006, PhD. Cecilia Hidalgo, who reflected on the incorporation of women into the world of science. The welcome to the seminar was given by PhD. Nicole Trefault, who recently assumed the Direction of Doctoral Programs, seconded by the Director of the Integrative Biology Program, PhD. Melissa Calegaro, who greeted the new students that incorporate to the Doctoral Program: Begoña Aranda, Camila Weiss, Felipe Grunenwald and Güilherme Gischkow Rucatti, the latter coming from Brazil.


In Addi...

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Center of Integrative Biology began seminar cycle with talks about cancer cell treatment

On this session of seminar, PhD. Matías Escobar, who is a researcher at the University of Pennsylvania explained the ability of certain cell signaling pathways to mediate the reactivation and proliferation of cancer cells.

In women, breast cancer is the first cause of death worldwide, according to information from the International Journal of Cancer and institutions dedicated to studying this disease. And for PhD. Matias Escobar-Aguirre, post-doctoral researcher in the Department of Cancer Biology at the University of Pennsylvania, this "mortality" is mainly linked to the metastatic recurrence that follows the initial treatment of cancer.

...

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Geroscience Center for Brain Health and Metabolism seeks motivated post-doctoral researchers

03-05-2019

Information about GERO available at www.gerochile.org

Topics include:

– Cytoskeleton dysfunction in aging and neurodegenerative diseases
– Proteostasis in aging and neurodegenerative diseases
– Axonal degeneration and regeneration in neurodegenerative diseases
– Age-dependent microbiome changes
– Mitochondrial dysfunction in aging and neurodegenerative diseases
– Novel models for aging research (Killifish, Droshopila, mice)
– Stem cell generation (iPSC) from human neurodegenerative conditions
– Neuropsychology of aging and neurodegeneratives diseases
– Aging: Psychosocial studi...

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Biome Therapeutics is looking for Lead Scientist

03-05-2019

Call for a researcher to work in Biome Therapeutics Company, Santiago, Chile.

Biome Therapeutics, a startup dedicated to develop innovative technology from the gut microbiome, calls interested parties to apply for a position as Lead Scientist for projects associated with the study of the human microbiome and its possible therapeutic effects.

Functions: The activities associated with this charge will be the development of high quality research in the area of analysis of gut microbiome, isolation of bacterial strains and studies of the effect of the microbiome in different cellular models "in vitro".

Requirements: professional degree or Bachelor's degree in...

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Center of Integrative Biology at Universidad Mayor seeks a Veterinary Technician

03-05-2019

The Center of Integrative Biology at Universidad Mayor (CIB-UM) is offering a position as Veterinary Technician associated to the FONDAP program of the Geroscience Center.

The selected professional must demonstrate experience and potential to develop the activities associated with the position, being able to fulfill the following functions:

Do the change of boxes, water fountains, grilles, in conjunction with washing crates, troughs and grids.
Prepare spare boxes in advance to the days of changing boxes, preparing enrichment material for autoclaving and then providing it to the mice.
Keep clean and in-order the dependencies of the animal facilities.
...

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With cutting-edge technology: Chilean study seeks to create the rejuvenating brain injection to fight Parkinson's

28-01-2019

A scientific team at the U. Mayor, led by Dr. René Vidal, works on a gene treatment to delay and reverse the symptoms of the disease.

By Gabriel Arce
Monday 28, January 2019

According to recent data from the Ministry of Health, more than 40 thousand Chileans live with Parkinson's. Therefore, the alert is a fact, since the World Health Organization (WHO) estimates that the number of pe...

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U. Mayor granted with 8 Fondecyt Projects for a total sum of CLP$1600m

18-01-2019

The scientific initiatives are aimed at the study of neurodegenerative diseases, aging, the development of ecosystems and genomics, among other areas.

A new and important achievement in research is the one that the Universidad Mayor has just obtained, after the awarding of 8 regular Fondecyt projects, which were presented by its Genomics, Ecology and Environment Centers (GEMA); Modeling and Monitoring of Ecosystems; Integrative Biology; Society and Health; and Optics and Quantum Information.

These initiatives represent 40% of the total of the works presented by this house of studies (20), higher than the national average, which reached an average of 20%.

It should be ...

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The effect of autophagy on brain health

22-11-2018

Source: HEUREKA
All Content under the Creative Commons Attribution-NonCommercial 4.0 International License of HEUREKA.


By Melissa Calegaro, PhD in Biomedical Sciences. Assistant Professor and Director of the Doctorate Program in Neurobiology Universidad Mayor.

I am an initial training pharmacist. However, since I started this career, the question I wanted to help answer was why our brain gets sick. In the second semester I asked to work as a volunteer in a laboratory during my free time. I wanted to learn about this organ and how to treat it in case of illness. From there I never left science, nor the ques...

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Scientists will use Drosophila for decoding Parkinson's symptoms

19-11-2018

René Vidal, Ph.D., Investigator at Center for Integrative biology from Umayor, talked about a work that is looking for decoding why Parkinson's symptoms are different among people.

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Can Aging be controlled? Check how our Center for Integrative Biology Works

08-11-2018

Check the interview with Dr. Felipe Court, who talks about Geroscience, an area which look for solve the mysteries of aging, pointing at common diseases.

Click for the first part of the interview https://www.litoralpress.cl/de...

In a new edition of ""Exploradores: Del Átomo al Cosmos", from 24 Horas Channel, the main topic is how science is working with the growing of life expectancy.

Click fot the second part of the interview https://www.litoralpress.cl/de...

Source: Diario Mayor.<...

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Center for Integrative Biology is awarded 2 projects "Fondecyt de Iniciación 2018", from the 13 awarded to Universidad Mayor.

31-10-2018

The two projects are the following:

DISSECTING THE ROLE OF VSX TRANSCRIPTION FACTORS IN THE DEVELOPMENT OF THE VERTEBRATE VISUAL SYSTEM.
The aim of this project is to study the cellular and regulatory impact over fish visual system formation upon Vsx transcription factors removal. 

ROLE OF RUBICON AND PACER IN RIPK1-DEPENDENT APOPTOSIS INDUCED BY TNF
The general aim of this project is to determine the role of two autophagy-regulatory proteins, Rubicon and Pacer, on cell death induced by TNF and to define their potential of therapeutic targets en Mesenchymal Stem Cells.

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Scientists from the Center for Integrative Biology at Universidad Mayor obtains two Conicyt projects for the formation of International Networks 2018.

22-10-2018

The grant entitled “Modelling human brain disorders using iPSCs and brain organoids” aims to create a network among the researchers Dr. Gonzalo Cancino, Dr. Melissa Calegaro and Dr. Leonardo Valdivia at the Center for Integrative Biology at Universidad Mayor in Chile and the UK based researchers Dr. Madeline Lancaster at University of Cambridge and Dr. Greg Findlay at University of Dundee. This network is focused in understanding how the human brain develops and how genes associated to neurodevelopmental disorders regulate human brain cortical development using human iPSCs, brain organoids and phospho-proteomic analysis.

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CIB investigator Carol San Martín talked about World Alzheimer´s Day

11-10-2018

CIB investigator Carol San Martín talked about World Alzheimer´s Day at Digital FM.

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Dr. Mario Sanhueza from the Center for Integrative Biology at Universidad Mayor obtains a project for insertion in the Academia.

05-10-2018

Conicyt´s grant Installation in the academy seeks to contribute to the institutional strengthening of national higher education entities, by hiring researchers who start their independent career, in order to close the gap between the last stages of doctoral training and their insertion in the academy

The installation proposal of Dr. Mario Sanhueza meets the guidelines of the development plan of the Center for Integrative Biology of the University, based on high quality science, a high level of scientific collaboration, and experience in teaching and outreach.


In his research project Dr. Sanhueza will try to understand mechanisms with the potential to delay the onse...

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Paola Murgas Ph.D. talks about Nobel Prize given to immunologists

01-10-2018

Yesterday, our Investigator Paola Murgas visited @Tele13_Radio and talked about the Nobel Prize, given to the immunologists James Allison and Tasuku Honjo, for discovering how to use our own cells to fight against cancer.


All rights reserved to Canal 13, content shared only for informative purposes.

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CIB Investigator conducting a research internship at Institut Curie, Paris, France

28-09-2018

Through an ECOS-Conicyt project association between Dr. Felipe Court Lab (CIB) and Christophe Lamaze Lab (Institute Curie), the investigator Cristian Saquel is conducting a research internship in Paris. He is studying the association between mechanic deformation of cells in NS and the liberation of molecular messages through extra cellular vesicles, a mechanism which could be related to tumours growth in NS.

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Felipe court, Ph.D. took part in the international congress organized by Spinal Research Foundation in UK.

07-09-2018

Felipe Court, Ph.D. took part in the International Congress organized by the Spinal Research Foundation in UK, one of the biggest foundations in that country that support researching related to SN regeneration, specially in spinal cord damage conditions. This international congress is made every year and the speakers are invited to show their findings. Dr. Court spoke about his investigation associated to SN regeneration and new information related to genetic networks which could participate in regeneration after spinal cord damage. This new findings could eventually be therapeutic targets to improve regeneration and functional regeneration after the damage to SN.

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Vice Chancellor explained the unknown role of bacteria in Alzheimer or food alergies.

03-09-2018

Patricio Manque, Ph.D in Microbiology & Inmunology from U. Federal do Sao Paulo (Brasil), offered a lecture in which highlighted the study in microbes as a "revolutionary tool" for medecine.

¿What does have in common Alzheimer and Periodontitis? ¿Cesarean and food alergies in kids? ¿Depresion and diet?. For Dr. Manque, Researching Vice Chancellor from U. Mayor, there's a created relationship. He stated so in the lecture "The super organism: How our microbes impact our health", offered this tuesday at GAM.

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Through lectures about the challenges of future, U.Mayor took part in "Protagonistas 2030"

31/08/2018

Also there was proposed a group of ideas to help to be prepared to a society more aged, like the investigation of this topic in an interdisciplinary way, joining public policies and personalized medicine; boost the early literacy for a healthy retirement, break the standard of the life course for a better functioning of elder stage; encourage the social and biological protection to break the chains that cause stress.

Dr. Manque offered a lecture about the human revolution of g...

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