Felipe Court

Fuentes-Flores, A., Geronimo-Olvera, C., Girardi, K., Necuñir-Ibarra, D., Patel, S. K., Bons, J., Wright, M. C., Geschwind, D., Hoke, A., Gomez-Sanchez, J. A., Schilling, B., Rebolledo, D. L., Campisi, J., & Court, F. A. (2023). Senescent Schwann cells induced by aging and chronic denervation impair axonal regeneration following peripheral nerve injury. EMBO Mol Med. https://doi.org/10.15252/emmm....

Díaz-Jara, E., Schwarz, K. G., Ríos-Gallardo, A., Toledo, C., Alcayaga, J. A., Court, F. A., & Del Rio, R. (2023). Carotid Body-Mediated Chemoreflex Function in Aging and the Role of Receptor-Interacting Protein Kinase. Adv Exp Med Biol, 1427, 195-201. doi:10.1007/978-3-031-32371-3_21

Arrázola, M. S., Lira, M., Véliz-Valverde, F., Quiroz, G., Iqbal, S., Eaton, S. L., Lamont, D. J., Huerta, H., Ureta, G., Bernales, S., Cárdenas, J. C., Cerpa, W., Wishart, T. M., & Court, F. A. (2023). Necroptosis inhibition counteracts neurodegeneration, memory decline, and key hallmarks of aging, promoting brain rejuvenation. Aging Cell, 22(5), e13814. doi:10.1111/acel.13814

Saquel, C., Catalan, R. J., Lopez-Leal, R., Ramirez, R. A., Necuñir, D., Wyneken, U., Lamaze, C., & Court, F. A. (2022). Neuronal activity-dependent ATP enhances the pro-growth effect of repair Schwann cell extracellular vesicles by increasing their miRNA-21 loading. Front Cell Neurosci, 16, 943506. doi:10.3389/fncel.2022.943506

Salvadores, N., Moreno-Gonzalez, I., Gamez, N., Quiroz, G., Vegas-Gomez, L., Escandón, M., Jimenez, S., Vitorica, J., Gutierrez, A., Soto, C., & Court, F. A. (2022). Aβ oligomers trigger necroptosis-mediated neurodegeneration via microglia activation in Alzheimer's disease. Acta Neuropathol Commun, 10(1), 31. doi:10.1186/s40478-022-01332-9

Kline, R. A., Lößlein, L., Kurian, D., Aguilar Martí, J., Eaton, S. L., Court, F. A., Gillingwater, T. H., & Wishart, T. M. (2022). An Optimized Comparative Proteomic Approach as a Tool in Neurodegenerative Disease Research. Cells, 11(17). doi:10.3390/cells11172653

Correa-Burrows, P., Burrows, R., Albala, C., Court, F. A., Salech, F., Sanhueza, G., & Gonzalez-Billault, C. (2022). Multiple events case-control study in a prospective cohort to identify systemic, cellular, and molecular biomarkers of obesity-induced accelerated aging in 30-years-olds: the ObAGE study protocol. BMC Geriatr, 22(1), 387. doi:10.1186/s12877-022-03032-4

Parra, M. A., Baez, S., Sedeño, L., Gonzalez Campo, C., Santamaría-García, H., Aprahamian, I., Bertolucci, P. H., Bustin, J., Camargos Bicalho, M. A., Cano-Gutierrez, C., Caramelli, P., Chaves, M. L. F., Cogram, P., Beber, B. C., Court, F. A., de Souza, L. C., Custodio, N., Damian, A., de la Cruz, M., Diehl Rodriguez, R., Brucki, S. M. D., Fajersztajn, L., Farías, G. A., De Felice, F. G., Ferrari, R., de Oliveira, F. F., Ferreira, S. T., Ferretti, C., Figueredo Balthazar, M. L., Ferreira Frota, N. A., Fuentes, P., García, A. M., Garcia, P. J., de Gobbi Porto, F. H., Duque Peñailillo, L., Engler, H. W., Maier, I., Mata, I. F., Gonzalez-Billault, C., Lopez, O. L., Morelli, L., Nitrini, R., Quiroz, Y. T., Guerrero Barragan, A., Huepe, D., Pio, F. J., Suemoto, C. K., Kochhann, R., Kochen, S., Kumfor, F., Lanata, S., Miller, B., Mansur, L. L., Hosogi, M. L., Lillo, P., Llibre Guerra, J., Lira, D., Lopera, F., Comas, A., Avila-Funes, J. A., Sosa, A. L., Ramos, C., Resende, E. P. F., Snyder, H. M., Tarnanas, I., Yokoyama, J., Llibre, J., Cardona, J. F., Possin, K., Kosik, K. S., Montesinos, R., Moguilner, S., Solis, P. C. L., Ferretti-Rebustini, R. E. L., Ramirez, J. M., Matallana, D., Mbakile-Mahlanza, L., Marques Ton, A. M., Tavares, R. M., Miotto, E. C., Muniz-Terrera, G., Muñoz-Nevárez, L. A., Orozco, D., Okada de Oliveira, M., Piguet, O., Pintado Caipa, M., Piña Escudero, S. D., Schilling, L. P., Rodrigues Palmeira, A. L., Yassuda, M. S., Santacruz-Escudero, J. M., Serafim, R. B., Smid, J., Slachevsky, A., Serrano, C., Soto-Añari, M., Takada, L. T., Grinberg, L. T., Teixeira, A. L., Barbosa, M. T., Trépel, D., & Ibanez, A. (2021). Dementia in Latin America: Paving the way toward a regional action plan. Alzheimers Dement, 17(2), 295-313. doi:10.1002/alz.12202

Oñate, M., Catenaccio, A., Martínez, G., Armentano, D., Parsons, G., Kerr, B., Hetz, C., & Court, F. A. (2021). Author Correction: Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury. Sci Rep, 11(1), 24424. doi:10.1038/s41598-021-04003-2

Lemaitre, D., & Court, F. A. (2021). New insights on the molecular mechanisms of collateral sprouting after peripheral nerve injury. Neural Regen Res, 16(9), 1760-1761. doi:10.4103/1673-5374.306069

Gorostieta-Salas, E., Moreno-Blas, D., Gerónimo-Olvera, C., Cisneros, B., Court, F. A., & Castro-Obregón, S. (2021). Enhanced Activity of Exportin-1/CRM1 in Neurons Contributes to Autophagy Dysfunction and Senescent Features in Old Mouse Brain. Oxid Med Cell Longev, 2021, 6682336. doi:10.1155/2021/6682336

Castillo, K., Rojas-Rivera, D., Lisbona, F., Caballero, B., Nassif, M., Court, F. A., Schuck, S., Ibar, C., Walter, P., Sierralta, J., Glavic, A., & Hetz, C. (2021). BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response. Embo j, 40(21), e109149. doi:10.15252/embj.2021109149

Slachevsky, A., Zitko, P., Martínez-Pernía, D., Forno, G., Court, F. A., Lillo, P., Villagra, R., Duran-Aniotz, C., Parrao, T., Assar, R., Orellana, P., Toledo, C., Rivera, R., Ibañez, A., Parra, M. A., González-Billault, C., Amieva, H., & Thumala, D. (2020). GERO Cohort Protocol, Chile, 2017-2022: Community-based Cohort of Functional Decline in Subjective Cognitive Complaint elderly. BMC Geriatr, 20(1), 505. doi:10.1186/s12877-020-01866-4

Salvadores, N., Gerónimo-Olvera, C., & Court, F. A. (2020). Axonal Degeneration in AD: The Contribution of Aβ and Tau. Front Aging Neurosci, 12, 581767. doi:10.3389/fnagi.2020.581767

Salvadores, N., & Court, F. A. (2020). The necroptosis pathway and its role in age-related neurodegenerative diseases: will it open up new therapeutic avenues in the next decade? Expert Opin Ther Targets, 24(7), 679-693. doi:10.1080/14728222.2020.1758668

Oñate, M., Catenaccio, A., Salvadores, N., Saquel, C., Martinez, A., Moreno-Gonzalez, I., Gamez, N., Soto, P., Soto, C., Hetz, C., & Court, F. A. (2020). The necroptosis machinery mediates axonal degeneration in a model of Parkinson disease. Cell Death Differ, 27(4), 1169-1185. doi:10.1038/s41418-019-0408-4

Martinez, N. W., Sánchez, A., Diaz, P., Broekhuizen, R., Godoy, J., Mondaca, S., Catenaccio, A., Macanas, P., Nervi, B., Calvo, M., & Court, F. A. (2020). Metformin protects from oxaliplatin induced peripheral neuropathy in rats. Neurobiol Pain, 8, 100048. doi:10.1016/j.ynpai.2020.100048

López-Leal, R., Díaz-Viraqué, F., Catalán, R. J., Saquel, C., Enright, A., Iraola, G., & Court, F. A. (2020). Schwann cell reprogramming into repair cells increases miRNA-21 expression in exosomes promoting axonal growth. J Cell Sci, 133(12). doi:10.1242/jcs.239004

López-Leal, R., & Court, F. A. (2020). Ex Vivo Analysis of Axonal Degeneration Using Sciatic and Optic Nerve Preparations. Methods Mol Biol, 2143, 179-189. doi:10.1007/978-1-0716-0585-1_14

Lemaitre, D., Hurtado, M. L., De Gregorio, C., Oñate, M., Martínez, G., Catenaccio, A., Wishart, T. M., & Court, F. A. (2020). Collateral Sprouting of Peripheral Sensory Neurons Exhibits a Unique Transcriptomic Profile. Mol Neurobiol, 57(10), 4232-4249. doi:10.1007/s12035-020-01986-3

García-Huerta, P., Troncoso-Escudero, P., Wu, D., Thiruvalluvan, A., Cisternas-Olmedo, M., Henríquez, D. R., Plate, L., Chana-Cuevas, P., Saquel, C., Thielen, P., Longo, K. A., Geddes, B. J., Lederkremer, G. Z., Sharma, N., Shenkman, M., Naphade, S., Sardi, S. P., Spichiger, C., Richter, H. G., Court, F. A., Tshilenge, K. T., Ellerby, L. M., Wiseman, R. L., Gonzalez-Billault, C., Bergink, S., Vidal, R. L., & Hetz, C. (2020). Insulin-like growth factor 2 (IGF2) protects against Huntington's disease through the extracellular disposal of protein aggregates. Acta Neuropathol, 140(5), 737-764. doi:10.1007/s00401-020-02183-1

Pérez, V., Bermedo-Garcia, F., Zelada, D., Court, F. A., Pérez, M., Fuenzalida, M., Ábrigo, J., Cabello-Verrugio, C., Moya-Alvarado, G., Tapia, J. C., Valenzuela, V., Hetz, C., Bronfman, F. C., & Henríquez, J. P. (2019). The p75(NTR) neurotrophin receptor is required to organize the mature neuromuscular synapse by regulating synaptic vesicle availability. Acta Neuropathol Commun, 7(1), 147. doi:10.1186/s40478-019-0802-7

Kline, R. A., Dissanayake, K. N., Hurtado, M. L., Martínez, N. W., Ahl, A., Mole, A. J., Lamont, D. J., Court, F. A., Ribchester, R. R., Wishart, T. M., & Murray, L. M. (2019). Altered mitochondrial bioenergetics are responsible for the delay in Wallerian degeneration observed in neonatal mice. Neurobiol Dis, 130, 104496. doi:10.1016/j.nbd.2019.104496

Escudero, C. A., Cabeza, C., Moya-Alvarado, G., Maloney, M. T., Flores, C. M., Wu, C., Court, F. A., Mobley, W. C., & Bronfman, F. C. (2019). c-Jun N-terminal kinase (JNK)-dependent internalization and Rab5-dependent endocytic sorting mediate long-distance retrograde neuronal death induced by axonal BDNF-p75 signaling. Sci Rep, 9(1), 6070. doi:10.1038/s41598-019-42420-6

Carreras-Sureda, A., Jaña, F., Urra, H., Durand, S., Mortenson, D. E., Sagredo, A., Bustos, G., Hazari, Y., Ramos-Fernández, E., Sassano, M. L., Pihán, P., van Vliet, A. R., González-Quiroz, M., Torres, A. K., Tapia-Rojas, C., Kerkhofs, M., Vicente, R., Kaufman, R. J., Inestrosa, N. C., Gonzalez-Billault, C., Wiseman, R. L., Agostinis, P., Bultynck, G., Court, F. A., Kroemer, G., Cárdenas, J. C., & Hetz, C. (2019). Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics. Nat Cell Biol, 21(6), 755-767. doi:10.1038/s41556-019-0329-y

Arrázola, M. S., Saquel, C., Catalán, R. J., Barrientos, S. A., Hernandez, D. E., Martínez, N. W., Catenaccio, A., & Court, F. A. (2019). Axonal Degeneration Is Mediated by Necroptosis Activation. J Neurosci, 39(20), 3832-3844. doi:10.1523/jneurosci.0881-18.2019

Arrazola, M. S., & Court, F. A. (2019). Compartmentalized necroptosis activation in excitotoxicity-induced axonal degeneration: a novel mechanism implicated in neurodegenerative disease pathology. Neural Regen Res, 14(8), 1385-1386. doi:10.4103/1673-5374.253520

Urra, H., Henriquez, D. R., Cánovas, J., Villarroel-Campos, D., Carreras-Sureda, A., Pulgar, E., Molina, E., Hazari, Y. M., Limia, C. M., Alvarez-Rojas, S., Figueroa, R., Vidal, R. L., Rodriguez, D. A., Rivera, C. A., Court, F. A., Couve, A., Qi, L., Chevet, E., Akai, R., Iwawaki, T., Concha, M. L., Glavic, Á., Gonzalez-Billault, C., & Hetz, C. (2018). IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A. Nat Cell Biol, 20(8), 942-953. doi:10.1038/s41556-018-0141-0

Poitelon, Y., Matafora, V., Silvestri, N., Zambroni, D., McGarry, C., Serghany, N., Rush, T., Vizzuso, D., Court, F. A., Bachi, A., Wrabetz, L., & Feltri, M. L. (2018). A dual role for Integrin α6β4 in modulating hereditary neuropathy with liability to pressure palsies. J Neurochem, 145(3), 245-257. doi:10.1111/jnc.14295

Müller, M., Ahumada-Castro, U., Sanhueza, M., Gonzalez-Billault, C., Court, F. A., & Cárdenas, C. (2018). Mitochondria and Calcium Regulation as Basis of Neurodegeneration Associated With Aging. Front Neurosci, 12, 470. doi:10.3389/fnins.2018.00470

López-Leal, R., Diaz, P., & Court, F. A. (2018). In Vitro Analysis of the Role of Schwann Cells on Axonal Degeneration and Regeneration Using Sensory Neurons from Dorsal Root Ganglia. Methods Mol Biol, 1739, 255-267. doi:10.1007/978-1-4939-7649-2_16

Hernández, D. E., Salvadores, N. A., Moya-Alvarado, G., Catalán, R. J., Bronfman, F. C., & Court, F. A. (2018). Axonal degeneration induced by glutamate excitotoxicity is mediated by necroptosis. J Cell Sci, 131(22). doi:10.1242/jcs.214684

Gonzalez, D., Rebolledo, D. L., Correa, L. M., Court, F. A., Cerpa, W., Lipson, K. E., van Zundert, B., & Brandan, E. (2018). The inhibition of CTGF/CCN2 activity improves muscle and locomotor function in a murine ALS model. Hum Mol Genet, 27(16), 2913-2926. doi:10.1093/hmg/ddy204

De Gregorio, C., Díaz, P., López-Leal, R., Manque, P., & Court, F. A. (2018). Purification of Exosomes from Primary Schwann Cells, RNA Extraction, and Next-Generation Sequencing of Exosomal RNAs. Methods Mol Biol, 1739, 299-315. doi:10.1007/978-1-4939-7649-2_19

Catenaccio, A., & Court, F. A. (2018). Teased Fiber Preparation of Myelinated Nerve Fibers from Peripheral Nerves for Vital Dye Staining and Immunofluorescence Analysis. Methods Mol Biol, 1739, 329-337. doi:10.1007/978-1-4939-7649-2_21

Salvadores, N., Sanhueza, M., Manque, P., & Court, F. A. (2017). Axonal Degeneration during Aging and Its Functional Role in Neurodegenerative Disorders. Front Neurosci, 11, 451. doi:10.3389/fnins.2017.00451

Martin, C., Leyton, L., Hott, M., Arancibia, Y., Spichiger, C., McNiven, M. A., Court, F. A., Concha, M. I., Burgos, P. V., & Otth, C. (2017). Herpes Simplex Virus Type 1 Neuronal Infection Perturbs Golgi Apparatus Integrity through Activation of Src Tyrosine Kinase and Dyn-2 GTPase. Front Cell Infect Microbiol, 7, 371. doi:10.3389/fcimb.2017.00371

Catenaccio, A., Llavero Hurtado, M., Diaz, P., Lamont, D. J., Wishart, T. M., & Court, F. A. (2017). Molecular analysis of axonal-intrinsic and glial-associated co-regulation of axon degeneration. Cell Death Dis, 8(11), e3166. doi:10.1038/cddis.2017.489

Castillo, K., Rojas-Rivera, D., Lisbona, F., Caballero, B., Nassif, M., Court, F. A., Schuck, S., Ibar, C., Walter, P., Sierralta, J., Glavic, A., & Hetz, C. (2017). BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response. Embo j, 36(11), 1640. doi:10.15252/embj.201797020

Bargsted, L., Medinas, D. B., Martínez Traub, F., Rozas, P., Muñoz, N., Nassif, M., Jerez, C., Catenaccio, A., Court, F. A., Hetz, C., & Matus, S. (2017). Disulfide cross-linked multimers of TDP-43 and spinal motoneuron loss in a TDP-43(A315T) ALS/FTD mouse model. Sci Rep, 7(1), 14266. doi:10.1038/s41598-017-14399-5

Valenzuela, V., Oñate, M., Hetz, C., & Court, F. A. (2016). Injury to the nervous system: A look into the ER. Brain Res, 1648(Pt B), 617-625. doi:10.1016/j.brainres.2016.04.053

Oñate, M., Court, F. A., & Hetz, C. (2016). Bursting the unfolded protein response accelerates axonal regeneration. Neural Regen Res, 11(6), 892-893. doi:10.4103/1673-5374.184453

Oñate, M., Catenaccio, A., Martínez, G., Armentano, D., Parsons, G., Kerr, B., Hetz, C., & Court, F. A. (2016). Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury. Sci Rep, 6, 21709. doi:10.1038/srep21709

Lopez-Leal, R., & Court, F. A. (2016). Schwann Cell Exosomes Mediate Neuron-Glia Communication and Enhance Axonal Regeneration. Cell Mol Neurobiol, 36(3), 429-436. doi:10.1007/s10571-015-0314-3

López-Leal, R., Alvarez, J., & Court, F. A. (2016). Origin of axonal proteins: Is the axon-schwann cell unit a functional syncytium? Cytoskeleton (Hoboken), 73(10), 629-639. doi:10.1002/cm.21319

González, C., Cánovas, J., Fresno, J., Couve, E., Court, F. A., & Couve, A. (2016). Axons provide the secretory machinery for trafficking of voltage-gated sodium channels in peripheral nerve. Proc Natl Acad Sci U S A, 113(7), 1823-1828. doi:10.1073/pnas.1514943113

Court, F. A., & Alvarez, J. (2016). Schwann Cell and Axon: An Interlaced Unit-From Action Potential to Phenotype Expression. Adv Exp Med Biol, 949, 183-201. doi:10.1007/978-3-319-40764-7_9

Calvo, M., Richards, N., Schmid, A. B., Barroso, A., Zhu, L., Ivulic, D., Zhu, N., Anwandter, P., Bhat, M. A., Court, F. A., McMahon, S. B., & Bennett, D. L. (2016). Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury. Elife, 5, e12661. doi:10.7554/eLife.12661

Bodaleo, F. J., Montenegro-Venegas, C., Henríquez, D. R., Court, F. A., & Gonzalez-Billault, C. (2016). Microtubule-associated protein 1B (MAP1B)-deficient neurons show structural presynaptic deficiencies in vitro and altered presynaptic physiology. Sci Rep, 6, 30069. doi:10.1038/srep30069

Pasten, C., Cerda, J., Jausoro, I., Court, F. A., Cáceres, A., & Marzolo, M. P. (2015). ApoER2 and Reelin are expressed in regenerating peripheral nerve and regulate Schwann cell migration by activating the Rac1 GEF protein, Tiam1. Mol Cell Neurosci, 69, 1-11. doi:10.1016/j.mcn.2015.09.004

Lener, T., Gimona, M., Aigner, L., Börger, V., Buzas, E., Camussi, G., Chaput, N., Chatterjee, D., Court, F. A., Del Portillo, H. A., O'Driscoll, L., Fais, S., Falcon-Perez, J. M., Felderhoff-Mueser, U., Fraile, L., Gho, Y. S., Görgens, A., Gupta, R. C., Hendrix, A., Hermann, D. M., Hill, A. F., Hochberg, F., Horn, P. A., de Kleijn, D., Kordelas, L., Kramer, B. W., Krämer-Albers, E. M., Laner-Plamberger, S., Laitinen, S., Leonardi, T., Lorenowicz, M. J., Lim, S. K., Lötvall, J., Maguire, C. A., Marcilla, A., Nazarenko, I., Ochiya, T., Patel, T., Pedersen, S., Pocsfalvi, G., Pluchino, S., Quesenberry, P., Reischl, I. G., Rivera, F. J., Sanzenbacher, R., Schallmoser, K., Slaper-Cortenbach, I., Strunk, D., Tonn, T., Vader, P., van Balkom, B. W., Wauben, M., Andaloussi, S. E., Théry, C., Rohde, E., & Giebel, B. (2015). Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper. J Extracell Vesicles, 4, 30087. doi:10.3402/jev.v4.30087

Castillo, V., Oñate, M., Woehlbier, U., Rozas, P., Andreu, C., Medinas, D., Valdés, P., Osorio, F., Mercado, G., Vidal, R. L., Kerr, B., Court, F. A., & Hetz, C. (2015). Functional Role of the Disulfide Isomerase ERp57 in Axonal Regeneration. PLoS One, 10(9), e0136620. doi:10.1371/journal.pone.0136620

Activo

2015-2025, FONDAP,15150012, (director e Investigador Principal)

2022-2024, FONDEF, ID20I10152, (director Alterno)

2021-2022, ANID, NAM21I0059, (Investigador Principal)

2021-2024, LiSIUM initiative, (Investigador Principal)

2023-2024, Internacional, MJFF-022678, (Investigador Principal)

2023-2027, FONDECYT,1231432, (Investigador Principal)

2023-2025, Chan Zuckerberg Initiative,2023-3212224 (5022) GB-1585623, (Investigador Principal)

Terminado

2007-2010, FONDECYT, 1070377, (Investigador Principal)

2009-2010, FONDECYT ,1090230, (Investigador Responsable)

2010-2013, FONDEF, D08I1031, (Investigador Principal)

2010-2013, FONDECYT, 1110523, (Investigador Responsable)

2010-2015, FONDECYT, 3110014, (Investigador Responsable)

2010-2015, Internacional, NASS, (Investigador Principal)

2011-2014, Núcleo Milenio, P07-011-F, (Investigador Responsable)

2011-2014, FONDECYT, 1110987, (Investigador Principal)

2012-2015, Internacional, CDR, (Investigador Principal)

2012-2015, FONDECYT ,3130610, (Investigador Responsable)

2012-2015, FONDECYT ,3130527, (Investigador Responsable)

2013-2015, FONDEF-Idea, CA12I10120, (Investigador Principal)

2013-2015, Anillo, ACT-1109, (Investigador Principal)

2013-2016, FONDECYT ,3140406, (Investigador Responsable)

2014-2016, Núcleo Milenio, RC120003, (Co- director)

2015-2018, FONDECYT ,1150766, (Investigador Principal)

2016-2019, Internacional,108192, (Investigador Principal)

2017-2020, ECOS,170010, (Investigador Principal)

2017-2019, FONDECYT ,3170577, (Investigador Responsable)

2018-2021, FONDECYT ,3180341, (Investigador Responsable)

2018-2021, FONDECYT ,3180313, (Investigador Responsable)

2018-2020, REDES,180126, (Investigador Principal)

2019-2021, Internacional, MJFF-009265, (Investigador Principal)

2019-2023, FONDECYT ,3190608, (Investigador Responsable)

2019-2023, FONDECYT,1190518, (Investigador Principal)

2021-2023, FONDECYT ,3210751, (Investigador Responsable)

Angel Landa, Lab Manager, Universidad Mayor.

Felipe Veliz Valverde, Estudiante Doctorado, Universidad Mayor.

Karina Girardi do Carmo de Vasconcelos, Postdoc, Universidad Mayor.

Rodrigo Ignacio Leiva Peñaloza, Asistente de Investigación, Universidad Mayor.

Daniela Victoria Rebolledo López, Center Manager. Asistente de Investigación Senior, Universidad Mayor.

Camila del Carmen Duran Opazo, Asistente de Investigación, Universidad Mayor.

Renata Sofia Gallardo Romero, Asistente de Investigación, Universidad Mayor.

Patricio Contreras, Estudiante Pregrado, Universidad Mayor.

Karina Angélica Reichel Fuentes, Asistente de investigación, Universidad Mayor.

Almendra Soto, Estudiante Pregrado, Universidad Mayor.

Valentina Nicole Manquez Inostroza, Estudiante Pregrado, Universidad Mayor.

Emmanuel Astudillo, Estudiante Pregrado, Universidad Mayor.

Fernanda Belén Araya Aliste, Estudiante Pregrado, Universidad Mayor.

Laura Gómez Gómez, Asistente de Investigación, Universidad Mayor.

Former Lab

Eileen Collyer, Postdoc, UCSD

Sebastián Barrientos, Bachelor in Biology, Ph,D

Juan S. Jara, Universite de Paris, Faculte des Sciences

David Cajas, 4th year Biochemistry student at Catholic

Diego Reginensi, MSc in Neuroscience

Rosario Villegas, Postdoc, PUC

Valeria Godoy, Postdoc

Vania Macias, Pregrado Student

Nicolas Martinez, Phd Student

Diego Hernández, PhD Student

Mónica Perez , Electron Microscopy

Claudia Carcamo, Research Assistant

Mario Sanhueza, Postdoctoral fellow

Mariela Araya, Postdoctoral fellow

Luis Valenzuela, Postdoctoral fellow

Cristian Valdebenito, Undergraduate Student

Pamela Rojas, Biochemistry student PUC

Javiera Villar, Biochemistry student at U. de Chile

Joaquín Cerca, Biochemist

Bruno Cisternas, MSc in Neuroscience

Cheryg Chavez, Lab. Manager

Álvaro Sánchez, Postdoc

Frederic Picou, Postdoc

Vicente Figueroa, Pregrado Student

Jaime Álvarez, Medical Doctor

Paula Diaz, Research Assistant

Claudia Orellana-Tavra, Postdoctoral fellow

Angelica Jaramillo,Research Assistant

Cristian Saquel, Research Assistant

Valentina Haro, Postdoctoral fellow

Gabriela Caceres, Research Assistant

Gerard Ill-Raga, Postdoctoral, Brazil

Alejandra López, P. Universidad Catolica de Chile

Vicente Valenzuela, MSc in Biotechnology.

Hugo Penailillo, Undergraduate student, Biology

Beatriz Díaz, Biologist

Fernanda Espinoza, Lab Manager

Constanza Miller, Lab Proyect

Alfredo Araneda, Pregrado Student

Carolina Chávez, Lab Manager

Cristian de Gregorio, Postdoctoral fellow

Maritza Oñate, PhD

Rodrigo López-Leal, Postdoctoral fellow

Alejandra Palma, Research Assistant

Victor Cueva, Research Assistant

Romina Catalán, Research Assistant

Natalia Salvadores, Postdoctoral fellow

Sergio Benites, Postdoctoral fellow

Alejandra Catenaccio, Research fellow

Macarena Arrazola, Postdoctoral fellow

Francisco Moya, Postdoctoral fellow

Cristian Geronimo, Postdoctoral fellow

Pedro Briceño, Research Assistant

Nicole Letelier, Postdoctoral fellow

Giannina Massoni, Research Assistant

Andres Fuentes, PhD Student

Francisco Muññoz, PhD Student

Enso Torres, PhD Student

David Necuñir, Research Assistant

José Manuel, Research Assistant

Genesis Vega, Postdoctoral fellow

National

Dr. Erick Riquelme, Profesor de la escuela de Medicina, Pontificia Universidad Católica de Chile, Chile.

Dr. Felipe Barros, Centro de estudios Científicos (CECS), Chile.

Dr. Macarena Arrázola, Centro de Biología Integrativa, Universidad Mayor, Chile.

Dr. Patricio Manque, Centro de Biología Integrativa, Universidad Mayor, Chile.

Dr. Margarita Calvo, programa doctoral en ciencias biológicas, Pontificia Universidad Católica de Chile, Chile.

Dr. Rodolfo Madrid, Facultad de química y bilogía, Universidad de Chile, Chile.

Dr. Sebastian Bernales, Fundación Ciencia y Vida, Chile.

Dr. Julio Cesar Cardenas, Centro de Biología Integrativa, Universidad Mayor, Chile.

Juan Pablo Henriquez, departamento de Biología Celular, Universidad de Concepción, Chile.

International

Dr. José Antonio Gomez-Sanchez, Instituto de Neurociencias, Universidad Miguel Hernandez de Elche, España.

Dr. Ahmet Hoke, Neuromuscular división profesor of Neurology, Johns Hopkins Outpatient Center, EE.UU.

Dr. Inés Moreno González, Dpto. Biología Celular, Genética y Fisiología, Universidad de Málaga, España.

Dr. Gregorio Iraola, Laboratorio de Genómica Microbiana, Institut Pasteur de Montevideo, Uruguay.

Dr. Christophe Lamaze, Institut Curie, Fracia.

Dr. Tom Wishart, The Roslin Institute, University of Edimburgh, Escocia.

Dr. Brigit Shilling, Buck Institute for Research on Aging, EE.UU.

Dr. Eric Verdin, Buck Institute for Research on Aging, EE.UU.